It said the bomb hit the entrance to the hospital.
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Central Command, which is responsible for US forces in the Middle East, said in a statement that the American-backed coalition had conducted air strikes in the area of Manbij during the past 24 hours and that it was looking into whether an air strike had resulted in civilian casualties.
They also said the journey to the frontline where the crossings were located was fraught with danger with snipers from both sides at times shooting at civilians.
“In this context, humanitarian corridors, which require residents of Aleppo to leave the city, do not represent a credible response to the situation”.
The reported crossings were the first major movement of people from the besieged eastern districts of the city, after Russian Federation and the Syrian government announced on Thursday a joint plan to open up three corridors to give civilians, as well as rebels willing to surrender, a way out.
According to Sana news agency, some rebel fighters have surrendered to government forces.
An AFP correspondent in east Aleppo said streets were empty on Friday morning, with residents holed up indoors. The bombings came a week after airstrikes, also blamed by Syrian activists on USA aircraft, killed at least 56 civilians in IS-held territory in northern Syria.
“Aleppo residents are calling the corridors that Russian Federation is talking about “death corridors”, he said. “The regime wants to say that civilians have left so it can burn Aleppo”.
Observatory’s chief Rami Adurrahman said another 13 people were killed in the strikes but that he could not say if they were Islamic State fighters or civilians.
About 300,000 people are trapped in rebel-held eastern Aleppo and the United Nations says food supplies are expected to run out in mid-August.
Dozens of fighters have laid down their weapons and surrendered, as the government’s military grip on rebel-held areas of the city tightens, it said.
In a statement issued on Friday, Bassma Kodmani, a member of the Syrian Opposition’s High Negotiations Committee, said: “The world must not allow Russian Federation to get away with disguising its assault on Aleppo with deceitful talk about humanitarian “corridors”. Forcing millions of civilians to live in inhumane conditions in Aleppo and other regions of Syria should be stopped immediately and the safety of people in those regions and access to humanitarian aid should also be provided under United Nations supervision, it added.
The US-based International Rescue Committee warned that those left behind in east Aleppo risked starvation and called for a pause in fighting.
“Aleppo residents are in distress and mistrustful, which is understandable, as the Syrian tragedy has shown that even humanitarianism is often used as a cynical ploy to advance geopolitical interests”.
The purported developments came two days after Russian Federation, an ally of Assad, announced four exit corridors were to be opened for both fighters and civilians.
Meanwhile, the U.S. has suggested the plan is a strategy to force civilians to leave and rebels to surrender.
The fate of Aleppo in the coming weeks has the potential to be a turning point in a seemingly endless, multi-sided civil war that has killed hundreds of thousands of people, driven millions from their homes and drawn in most world and regional powers.
Save the Children says the maternity hospital is the only such facility in the area, with the next facility some 70 kilometers (44 miles) away.
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It said there was an unspecified number of casualties.
