Lilly says it is excited by the results reported at the Alzheimer’s Association worldwide Conference (AAIC), although it stressed the findings are not in themselves evidence of efficacy but rather back up the “delayed-start” design used another study – EXPEDITION 3 – that is testing the drug in mild AD patients.
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The new study was presented at the Alzheimer’s Association global Conference in Washington, and the researchers have no leads on why gender is a possible cause of the disease.
It is an aerobic exercise that is cost-effective and free from side effects. Participants were assigned to either a group taking part in a supervised exercise program for 16 weeks or a control group.
One of the studies has unveiled that a therapy has proved to be quite beneficial. The program also improved attention, planning and organizing skills. The researchers found that participants who took aerobics significantly improved their memory and selective attention, compared with those not asked to exercise regularly.
Even among subjects who attended less frequently or exercised at lesser intensities, the aerobic conditioning classes drove down rates of anxiety, irritability and depression, hard neuropsychiatric symptoms that are common in those with Alzheimer’s disease, and distressing to both patients and their caregivers.
Women developing small but detectable deficits in memory and mental acuity in later parts of their lives eventually will be declining faster than men with wild impairment, as reported by researchers on Tuesday.
Another study also involved elderly with cognitive impairment. “No now approved medication can rival these effects”.
The drug, solanezumab, can slow cognitive and functional declines in those with mild cognitive impairment.
“These findings are important because they strongly suggest a potent lifestyle intervention such as aerobic exercise can impact Alzheimer’s-related changes in the brain”, says study co-author Laura Baker.
“These findings also highlight the potential value of non-drug therapies for Alzheimer’s disease and other dementias, and remind us that research ought to adamantly pursue combination and multi-modal approaches to Alzheimer’s therapy and prevention”, concludes Carrillo.
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For a long time, it remained largely unknown for scientists whether regular physical activity among Alzheimer’s patients could help improve symptoms of the disease, or if it could provide them with a positive impact regarding their brain’s physical changes as a result of the disease.
