Both the Saturday crashes on the interstate between Old Lyme and Old Saybrook involved tractor-trailers.
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One person has been killed in the second accident and crews have declared it a mass casualty scene because of the number of victims involved.
Interstate 95 remains closed in both directions in Old Lyme following a truck fire on one side of the highway and a serious, multi-vehicle crash on the other side.
Life Star and multiple ambulances transported patients to the hospital.
The first crash involving a tractor trailer occurred about 4:30 a.m. on southbound I-95 near the Whipporwill Road overpass, according to police.
NBC Connecticut reported via Facebook and Twitter that Life Star was also called to the second accident scene.
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News 8 has a crew on the way and will bring you more information as we receive it.
