To confirm their findings, the researchers conducted a similar study of 1,731 people from the Netherlands.
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Further analysis revealed that expression of the PDSS2 gene appeared to inhibit the body’s ability to break down caffeine.
An worldwide team of researchers has discovered a gene that is linked to the regulations of our coffee consumption, a study says.
Some people can’t start their day without a hot cup of coffee and now to support the same scientists have identified a gene that may explain why some people drink more coffee than others.
Coffee is one of the most popular beverages worldwide, second only to tea and water, researchers say.
Here, they assessed the genetic profile of 370 subjects living in Puglia in southern Italy. This plant was exported from Africa to countries around the world and coffee plants are now cultivated in over 70 countries, primarily in the equatorial regions of the Americas, Southeast Asia, India, and Africa.
The team found people with the PDSS2 DNA variation tended to consume fewer cups of coffee than people without the variation, a difference equivalent to one fewer cup daily on average. Though the result was same, but people with gene variation and without opted less number of coffee mugs. In Italy, people tend to drink smaller cups such as espresso whereas in the Netherlands the preference is towards larger cups that contain more caffeine overall.
That’s where they were able to find that the people who had the PDSS2 variation were likely to consume a cup of coffee less than those who didn’t have the variation.
If you consume numbers of cups of coffee in a day, then researchers have the reason for this. The gene is thought to regulate the production of proteins that metabolize caffeine in the body, the study authors report.
A recent study involving over 120,000 people confirmed the influence of CYP1A1-CYP1A2 and AHR and the existence of 6 new genes.
That urge for a mid-afternoon coffee hit could be partly genetic, according to a new study on Italian and Dutch drinkers..
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“We believe to have added an important piece to the understanding of the genetic basis behind coffee consumption and potentially to the mechanisms regulating caffeine metabolism”, the study said.
