Researchers have studied 145,456 children born in Quebec from 1999 to 2009.
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In the USA, about 2.2% of children ages 3 to 17 – about one in 45 – have autism, according to the Center for Disease Control and Prevention’s National Health Interview Survey, conducted in 2014.
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For women who took antidepressants in their first trimester, the risk went up to 1 per cent, and rose further to 1.2 per cent for those who had taken the pills in their second or third trimester. A total of 31 children (1.2 percent of 2,532) who were exposed to antidepressants during the second and third trimester were diagnosed with autism, while 40 children (1.0 percent of 4,200) exposed during the first trimester later received an autism diagnosis.
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Among those infants exposed to antidepressants in the first trimester, 1 percent were diagnosed with autism.
A study revealed on Monday shows women who take particular common antidepressants while with child may face almost twice the risk of giving birth to a child with autism.
Put another way, seven in 1,000 children without antidepressant exposure were diagnosed with ASD, compared to about 12 in 1,000 with mid- to late-pregnancy antidepressant exposure, said Barbara Mintzes, a pharmacology expert at the University of Sydney who was not involved in the study.
Earlier studies have found that depression, by itself, may already increase the risks for developing autism in the child. While vaccines have been proven time and time again to have no relation to autism whatsoever, researchers at the University of Montreal believe they may have found a link between autism and a different medicine: Antidepressants.
They found that the children of women who took antidepressants during the second and/or third trimester were at an 87 percent higher risk to develop autism than those without exposure. Even with the heightened risk identified in the JAMA Pediatrics study, the vast majority of pregnant women who took antidepressants did not haves babies with autism spectrum disorder.
Researchers at the University of Montreal have made a stunning discovery: Taking certain kinds of antidepressants in the later stages of pregnancy can increase the child’s risk of autism by as much as 87%. Pregnant women with uncontrolled depression may not eat well or keep up with prenatal visits, and, in the most severe cases they may be at increased risk for suicide.
“However, it is certainly advocating treatment of depression with something other than antidepressants during pregnancy”, Berard clarified.
No one really knows why rates of autism, or autism spectrum disorder (ASD), have roughly doubled over the past 10 years.
In one 2004 study published in Science, researchers gave pregnant mice SSRIs, and they observed notable biochemical differences in the offspring.
The causes of autism spectrum disorder are mysterious. Treating depression is important for a healthy pregnancy, since mentally healthy mothers will be better able to take care of themselves and their growing babies.
Deciding whether to keep taking antidepressants during pregnancy is a hard decision for women struggling with depression, Manevitz said.
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Berard said the findings do not prove the drugs are among the causes of the neurodevelopmental disorder in children – although some previous studies also pointed to the drugs as a possible culprit.
